WHAT IS CBD (CANNABIDIOL)?It’s not a stretch to say that CBD (cannabidiol) is one of the most exciting and promising compounds currently undergoing rigorous medical and scientific research. CBD has made headlines in recent years for some pretty stunning results.
Still, misinformation and confusion about CBD abounds due to the relatively recent emergence and widespread awareness of this incredible compound. Let’s take a deep dive into what cannabidiol (CBD) is, and exactly what it does -- and doesn’t -- do.
WHAT DOES CBD STAND FOR?CBD is simply short for “cannabidiol”, the second-most abundant cannabinoid molecule produced by the cannabis or hemp plant. The most abundant molecule, of course, being THC: the psychoactive chemical famous for making users feel “high” (CBD does not have this effect). Keep in mind that your body already has an endocannabinoid system, an extremely important molecular system that your body uses to regulate and perform various critical functions. CBD binds to receptors in this system; our bodies were designed to interface with cannabinoids from the very beginning -- we even naturally produce them!
CANNABIDIOL (CBD) FACTS
HOW DOES CBD WORK?As we stated earlier, your body already has a wildly complex endocannabinoid system that affects several different areas and functions. That system is rife with “receptors,” sites that await cannabinoid molecules presence. When the cannabinoid nears, the receptor will bind it to itself, creating a sophisticated chemical interaction that modern science is only just beginning to scratch the surface of understanding.
- CBD does not get you “high” (non-psychoactive)
- Comes from hemp or cannabis plants
- Potential medical applications include anxiety and pain relief
- Indirectly interacts with CB1 and CB2 cannabinoid receptors
- CBD is legal to buy and own
Unlike its sister molecule THC, CBD does not make you feel high -- but don’t think that a lack of psychoactive or intoxicating effect means that nothing is occurring. On the contrary, it’s very clear that there are many chemical responses that occur when CBD binds to those cannabinoid receptors. That being said, the endocannabinoid system is ubiquitous in the human body, affecting nearly all major functions in some way (especially homeostatic regulation). Because of this, it’s quite a task to discern everything that CBD does, exactly, when the binding occurs. That’s where the research is at right now: trying to solve that very mystery. CBD VS THCThough they share the same source plant family (cannabis), there is a huge difference between CBD and THC -- both in the effect they have and the way they chemically interact with your body. Until recently, CBD was somewhat stigmatized and not taken seriously as a potential medically therapeutic agent due to its chemical proximity to THC (the chemical that creates an intoxicating “high”). Let’s set the record straight once and for all.
- Not psychoactive/intoxicating
- Possible anti-anxiety applications
- Legal to buy and own
- Indirect agonist of cannabinoids
- Binds to the allosteric receptor site
- Legal to buy and own in the USA
Will I get “high” if I consume CBD?
- Highly psychoactive/intoxicating
- Has been shown to cause anxiety in some users
- Still illegal in some parts of the USA
- Directly binds to CB1 and CB2 receptors
- Binds to the orthosteric receptor site
- Legality varies from state to state
WHAT IS CBD OIL USED FOR?
- No, you will not get high from consuming CBD. It is made entirely and only from industrial hemp, and does not contain the psychoactive properties of THC. Additionally, cannabidiol actually has the property of being anti-psychoactive.
- Before we discuss some uses for CBD oil, we should clear up one area of confusion: what is CBD hemp oil, exactly? CBD hemp oil is simply the natural extracted oil product of the hemp plant, a non-psychoactive species of the cannabis family. Although CBD oil can also be derived from the psychoactive species as well, those oils can end up containing higher traces of THC, which is not ideal for all CBD users.
- Humans’ endocannabinoid system, which CBD directly affects, has a profound influence on a myriad of different areas and functions in our body. Therefore, CBD oil is being self-administered as a supplement by people all over the world to combat conditions.
- The fact is that new medical research is being performed on CBD every single day, and we don’t quite know definitively how it works -- but the potential is astounding. The financial sector is certainly betting on CBD hemp oil’s continued popularity: a recent Forbes article estimated that the CBD market will grow 700% by 2020.
Is CBD Legal?
Yes — although CBD comes from the cannabis plant family like its intoxicating cousin compound THC, you will not feel a “high” or psychoactive effect from CBD. Although there are tiny trace amounts of THC in most CBD products, the amount is so low that it is functionally impossible to get intoxicated from it. Therefore, CBD is legal to purchase and own across the United States. You can shop for CBD products with full confidence (and at CBDfx, we provide unique batch lab reports so that you can see exactly what you’re putting in your body, and in what proportion).
How long does it take CBD to take effect?
At the right dosage, it typically takes between 20 and 30 minutes for the CBD effects to be noticeable. As CBD has no psychoactive component, there is no ‘high’. You may experience a reduction in pain, reduced tremor, a sense of calm. It does depend on why you are taking CBD oil and whether you are taking enough to combat the symptoms you have and whether CBD has an effect on you.
What Are Some CBD Side Effects?
By all measurable results, CBD is extremely safe for humans to ingest. In fact, clinical trial data published by the journal Current Pharmaceutical Design showed that oral administration of CBD is safe even in extremely high doses.
That being said, some users do report mild side effects when using CBD. CBD will affect everyone differently, and you should always consult with your physician before beginning to supplement with CBD. Even when you do begin dosing with CBD, you should start with a small dose and work your way up until you understand how CBD affects your unique physiology.
Mild side effects from CBD are usually reported by users who took relatively high doses. Drowsiness or grogginess was the most common of these side effects. More than this, however, the most important consideration before taking CBD is to determine how it interacts with any drugs you are currently on. CBD may interfere with the way your drug regimen is working, so it’s critical that you have a conversation with your doctor to confirm that it’s appropriate to begin using CBD on your own.
Does CBD Get You High?
No — CBD will not get you “high” like the other famous chemical compound found in cannabis (THC). However, just because it doesn’t give you a “body buzz” or intoxicating high does not mean that you won’t feel an effect from taking CBD. The most commonly reported effects include a general sense of well-being or anxiety reduction, or a calm clarity of focus. Regardless, there is no intoxication involved. The World Health Organization has determined that there is no potential for abuse in terms of CBD usage.
What Does CBD Feel Like?
CBD affects everyone differently, but don’t go into your first CBD dose expecting to feel a “body high” or effect similar to THC-rich cannabis. It simply doesn’t work that way. THC binds directly to your CB1 and CB2 receptors; CBD, on the other hand, acts as a sneaky indirect agonist of cannabinoid receptors. That all means, in layman’s terms, that you won’t “feel” a prominent effect from taking CBD.
In fact, for many CBD users, it’s more about what they don’t feel when they dose CBD. Many people report that they feel calmer, with less anxiety, more able to fall asleep, and less agitated or irritable. And of course, many people also swear by CBD’s ability to alleviate or resolve chronic pain and inflammation issues.
What is the difference between Hemp Oil, CBD Oil and Hemp Extract?
CBD oil is produced from the whole plant – Leaves, stalks, flowers and seeds. Some CBD oils sold are Hemp oil is produced from hemp seeds only. Hemp extract is made from the whole plant.
What Is CBD Good For?
This is the million dollar question: what can CBD be used for? Before we dive into some of the uses, we need to make clear the fact that CBD research is in its infancy, and there are only a handful of definitive CBD studies right now. Therefore, it would be highly irresponsible to suggest that CBD is definitely or directly linked to any of these potential applications. Right now, CBD usage is wide open, and people are self-treating for a wide variety of symptoms.
Will CBD products interact with other medications or supplements?Like any other supplement, we advise that you contact your primary care physician for information regarding any drug interactions.What is the Standard Use and Serving Size?DOSING CBD OILEverybody’s endocannabinoid system is different, so dosage can vary. That is to say, that some will find relief with 3mg twice a day, while others are closer to 200mg four times a day or higher!
Pain and Inflammation Relief
One of the most highly researched potential applications of CBD right now is its analgesic effect. It’s likely that CBD disrupts pain receptors, paradoxically triggering release of dopamine and serotonin instead. There’s evidence to suggest that this can work even in patients for whom pharmaceutical options aren’t working, or for whom it isn’t safe to prescribe them.
One of the most popular reasons people purchase products on CBDfx.com, according to reviews and anecdotal user reports, is for anxiety relief. CBD has even been shown to counteract many of the effects of THC, including reduction of paranoia, stress, and anxiety. Several studies have already demonstrated measurable anxiety reduction from CBD usage based on biometric data while participants engaged in public speaking.
Via indirect agonism of 5-HT(1A), CBD has been shown to attenuate vomiting and nausea-related behavior according to a 2012 study. CBD indirectly activates autoreceptors in the dorsal raphe nucleus, which produces an anti-emetic (anti-nausea) effect. This can be an unspeakable relief for people who are experiencing nausea for a wide variety of reasons.
CBD is often discussed as part of a potential future treatment for schizophrenia and other forms of psychosis. The compound has been shown to induce a calming, anti-psychotic property in both humans and animals in more than one study.
Particularly when it comes to the cessation of eczema and acne, CBD oil (used as a topical treatment) is becoming increasingly popular. It’s thought that CBD’s anti-inflammatory potential could work synergistically with its positive effect on skin appearance and health.
CBD can have a sedative effect, particularly at higher doses. If you’ve ever suffered from insomnia or a condition that was keeping you from falling asleep, you know what a relief it can be to finally drift off for even a few hours.
WORKING UP TO THE RIGHT DOSEThe best way to find a proper dosage is to start low and slow and keep adjusting. For those new to cannabis, maybe try dosing at 5mg as needed to maintain relief. If multiple doses were taken during the first day, adjust the dose to 10mg and take note to any changes in effect. Keep adjusting as needed until relief is consistent. For those more experienced with cannabis, they may want to start at a higher dose, like 25mg, and adjust from there.
PATIENCE IS DUESome people require very small doses, while some still will feel nothing after a large dose. People also have different reactions to the various methods of use. It may take time to find the proper dosage and delivery method of CBD products to find the needed relief, so be patient. Some effects may be felt immediately, while others take a while to “build up” (particularly when looking for relief from epilepsy).*Persons who suspect they may have a disease or are seeking help for a specific disease should consult a qualified medical professional.